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References   References 219  
Type : Journal
Web link : https://doi.org/10.1046/j.1365-2710.1997.10475104.x
Research teams : Paris - Pharmacie centrale des hôpitaux de Paris
Authors : Oustric-Mendes AC, Huart B, Le Hoang MD, Perrin-Rosset M, Pailler FM, Darbord JC, Prognon, Gard C, Pradeau D.
Title : Study protocol : stability of morphine injected without preservative, delivered with a disposable infusion device.
Reference : J Clin Pharm Ther ; 22: 283-290. 1997
Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products identified and quantified
No visual inspection
List of drugs
InjectionMorphine hydrochloride Analgesic
Stability in solutions Polyisoprene elastomer Sodium chloride 0,9% 2,5 & 5 mg/ml 25°C Protect from light
30 Day
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