Last update :
28/04/2024
References   References 2131  
Type : Journal

Research teams : Bondy - University Hospital Jean Verdier, Department of Pharmacy
Authors : Sahraoui L, Chiadmi F, Schlatter J, Toledano A, Cisternino S, Fontan JE.
Title : Stability of voriconazole injection in 0.9% sodium chloride and 5% dextrose injections.
Reference : Am J Health-Syst Pharm ; 63: 1423-1426. 2006

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Imperfect separation of the internal standard from the product under study or its degradation products, or understudied
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Degradation products not observed in real conditions

List of drugs
InjectionVoriconazole Antifungal
Stability in solutions Polyolefine Sodium chloride 0,9% 2 mg/ml 25°C Protect from light
8 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 2 mg/ml 4°C Protect from light
8 Day
Stability in solutions Polyolefine Glucose 5% 2 mg/ml 25°C Protect from light
4 Day
Stability in solutions Polyolefine Glucose 5% 2 mg/ml 4°C Protect from light
6 Day

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