Last update :
14/06/2024
References   References 2118  
Type : Journal
Web link : https://www.sciencedirect.com/science/article/pii/S0885392406002648

Research teams : Villejuif - Institut Gustave Roussy, Department of Pharmacy
Authors : Chapalain-Pargade S, Laville I, Paci A, Chachaty E, Mercier L, Bourget Ph.
Title : Microbiological and physicochemical stability of fentanyl and sufentanil solutions for patient-controlled delivery-systems.
Reference : J Pain Symptom Manage ; 32, 1: 90-97. 2006

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Mass balance Measurement of osmolality PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Repeatability / reproducibility / standard range: results not provided or results outside specified values

List of drugs
InjectionFentanyl citrate Analgesic
Stability in solutions Polyvinyl chloride None 50 µg/ml 25°C Not specified
14 Day
InjectionSufentanil citrate Analgesic
Stability in solutions Polyvinyl chloride None 0,05 mg/ml 25°C Not specified
14 Day

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