Last update :
28/04/2024
References   References 2034  
Type : Journal
Web link : http://archive.eahp.eu/EJHP-Science-archive/Issue-5-2005

Research teams : Mont Godinne - Drug Stability Research Group (DSRG) - CHU UCL NAMUR, site de Godinne
Authors : Rodenbach MP, Hecq JD, Vanbeckbergen D, Jamart J, Galanti L.
Title : Effect of freezing, long-term storage and microwave thawing on the stability of vancomycin hydrochloride in 5% dextrose infusions.
Reference : EJHP Science ; 11, 5: 111-113. 2005

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 
Increased concentration unexplained
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
No comments for the degradation products

List of drugs
InjectionVancomycin hydrochloride Antibiotic
Stability in solutions Polyethylene Glucose 5% 5 mg/ml -20°C Protect from light
105 Day
Stability in solutions Polyethylene Glucose 5% 5 mg/ml 4°C Protect from light
56 Day

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