Last update :
28/04/2024
References   References 1995  
Type : Journal

Research teams : Los Angeles - University of Southern california, School of Pharmacy
Authors : Chin A, Liu S, Ting-Chan J, Gill MA.
Title : Extended stability of ascorbic acid in 5% dextrose injection and 0.9% sodium chloride injection.
Reference : Am J Health-Syst Pharm ; 62: 1073-1074. 2005

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Increased concentration unexplained

List of drugs
InjectionAscorbic acid Vitamin
Stability in solutions Not specified Sodium chloride 0,9% 9,3 mg/ml 23-25°C Protect from light
24 Hour
Stability in solutions Not specified Glucose 5% 7,8 mg/ml 23-25°C Protect from light
24 Hour

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