Last update :
03/05/2024
References   References 1989  
Type : Journal

Research teams : Paris - European University Hospital Georges Pompidou
Authors : Hennere G, Havard L, Bonan B, Prognon P.
Title : Stability of cidofovir in extemporaneously prepared syringes.
Reference : Am J Health-Syst Pharm ; 62: 506-509. 2005

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
Degradation products not observed in real conditions

List of drugs
InjectionCidofovir Antiviral
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 6.25 mg/ml 25°C With or without light
150 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 6.25 mg/ml 32°C With or without light
150 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 6.25 mg/ml 4°C Protect from light
150 Day

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