Last update :
18/04/2024
References   References 1936  
Type : Journal
Web link : https://doi.org/10.1345/aph.1D509

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Xu QA.
Title : Physical and chemical stability of palonosetron HCl in 4 infusion solusions.
Reference : Ann Pharmacotherapy ; 38: 1608-1611. 2004

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
InjectionPalonosetron hydrochloride Antiemetic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 & 30 µg/ml 23°C Light
48 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 & 30 µg/ml 4°C Protect from light
14 Day

  Mentions Légales