Last update :
28/02/2024
References   References 1857  
Type : Journal
Web link : https://doi.org/10.1016/S0731-7085(99)00057-6

Research teams : Rome - Istituto Superiore di Sanita, Laboratorio di Chimica del Farmaco
Authors : Farina A, Porra R, Cotichini V, Doldo A.
Title : Stability of reconstituted solutions of ceftazidime for injections: an HPLC and CE approach.
Reference : J Pharm Biomed Anal ; 20-521-530. 1999

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Capillary electrophoresis
Ultraviolet spectrometry
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
No visual inspection
Degradation products identified and quantified

List of drugs
InjectionCeftazidime Antibiotic
Factors which affect stability Temperature Increase Induces Degradation
Stability in solutions Glass Water for Injection 270 mg/ml 20°C With or without light
18 Hour
Stability in solutions Glass Water for Injection 270 mg/ml 4°C Not specified
7 Day

  Mentions Légales