Last update :
18/04/2024
References   References 1817  
Type : Journal
Web link : http://opp.sagepub.com/cgi/content/abstract/9/2-3/109

Research teams : Bath - Department of Pharmacy & Pharmacology
Authors : Roberts S, Sewell GJ.
Title : Stability and compatibility of 5-fluorouracil infusions in the Braun Easypump®.
Reference : J Oncol Pharm Practice ; 9: 109-112. 2003

Level of Evidence : 
Level of evidence C
Physical stability : 
Visual examination Particle counting 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
No comments for the degradation products

List of drugs
InjectionFluorouracil Anticancer drug
Stability in solutions Silicone elastomer NaCl 0,9% or Glucose 5% 25 mg/ml 25°C Not specified
21 Day
Stability in solutions Silicone elastomer NaCl 0,9% or Glucose 5% 25 mg/ml 31°C Not specified
21 Day
Stability in solutions Silicone elastomer NaCl 0,9% or Glucose 5% 25 mg/ml 4°C Not specified
14 Day
Stability in solutions Silicone elastomer None 50 mg/ml 25°C Not specified
21 Day
Stability in solutions Silicone elastomer None 50 mg/ml 31°C Not specified
21 Day

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