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References   References 1806  
Type : Journal
Web link : https://www.cjhp-online.ca/index.php/cjhp/article/view/584
Research teams : Ottawa - The Ottawa Hospital, department of Pharmacy
Authors : Donnely RF.
Title : Chemical stability of dimenhydrinate in minibags and polypropylene syringes.
Reference : Can J Hosp Pharm ; 55, 5: 307-312. 2002
Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
List of drugs
injectionDimenhydrinate Antihistamine (H1)
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 >> 2 mg/ml 22°C Light
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 0,5 >> 2 mg/ml 4°C Protect from light
91 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 2,5 >> 10 mg/ml 22°C Light
60 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 2,5 >> 10 mg/ml 4°C Protect from light
60 Day
Compatible + Sodium chloride 0,9%
Compatible + Glucose 5%
  Mentions Légales