Last update :
28/04/2024
References   References 1750  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=1121

Research teams : Ottawa - The Ottawa Hospital, department of Pharmacy
Authors : Donelly RF, Bushfield TL.
Title : Chemical stability of meperidine hydrochloride in polypropylene syringes.
Reference : Int J Pharm Compound ; 2: 463-465. 1998

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
InjectionPethidine hydrochloride Analgesic
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,25 & 30 mg/ml 22°C Protect from light
28 Day
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 0,25 & 30 mg/ml 4°C Protect from light
28 Day

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