Last update :
03/05/2024
References   References 1709  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=348

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Trissel LA, Xu QA.
Title : Physical and chemical stability of morphine sulfate 5 mg/ml and 50 mg/ml packaged in plastic syringes.
Reference : Int J Pharm Compound ; 6: 62-65. 2002

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 

List of drugs
InjectionMorphine sulfate Analgesic
Stability in solutions Polypropylen Syringe Water for Injection 50 mg/ml 23°C Protect from light
60 Day
Stability in solutions Polypropylen Syringe Water for Injection 50 mg/ml 37°C Protect from light
48 Hour
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 5 mg/ml 4°C Protect from light
60 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 5 & 50 mg/ml 23°C Light
60 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 5 & 50 mg/ml 37°C Protect from light
48 Hour

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