Last update :
16/01/2021
References   References 1704  
Type : Journal
Web link : http://www.ijpc.com/Abstracts/Abstract.cfm?ABS=800

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Xu QA, Trissel LA, Saenz A.
Title : Stability of gentamicin sulfate and tobramycin sulfate in autodose infusion system bags.
Reference : Int J Pharm Compound ; 6: 152-154. 2002

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Turbidimetry Particle counting 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
Comments : 
No comments for the degradation products

List of drugs
InjectionGentamicin sulfate Antibiotic
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 0,85 mg/ml 23°C Protect from light
7 Day
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 0,85 mg/ml 4°C Protect from light
30 Day
InjectionTobramycin sulfate Antibiotic
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 0,95 mg/ml 23°C Protect from light
7 Day
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 0,95 mg/ml 4°C Protect from light
30 Day

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