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References   References 1671  
Type : Journal
Research teams : Nimes - Caremeau Hospital, Pharmacy Department
Authors : Khalfi F, Dine T, Gressier B, Luyckx M, Brunet C, Ballester L, Goudaliez F, Cazin M, Cazin JC.
Title : Compatibility and stability of vancomycin hydrochloride with PVC infusion material in various conditions using stability-indicating high-performance liquid chromatographic assay.
Reference : Int J Pharm ; 139: 243-247. 1996
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
Search of DEHP 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point
Degradation products not observed in real conditions
List of drugs
InjectionVancomycin hydrochloride Antibiotic
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 mg/ml 22°C Light
48 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 5 mg/ml 4°C Protect from light
7 Day
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