Last update :
03/05/2024
References   References 1663  
Type : Journal

Research teams : Barcelona - Institut Català d’Oncologia, Pharmacy Department
Authors : Ponton JL, Munoz C, Rey M, Val M.
Title : The stability of (lyophilized) gemcitabine in 0.9% sodium chloride injection.
Reference : EJHP ; 1: 23-25. 2002

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
No comments for the degradation products

List of drugs
InjectionGemcitabine hydrochloride Anticancer drug
Stability in solutions Glass Sodium chloride 0,9% 40 mg/ml 25°C With or without light
27 Day
Stability in solutions Glass Sodium chloride 0,9% 7,5 & 25 mg/ml 25°C With or without light
27 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 7,5 & 25 mg/ml 25°C With or without light
27 Day

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