Last update :
27/10/2020
References   References 1613  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Lepage R, Walker SE, Godin J.
Title : Stability and compatibility of etoposide in normal saline.
Reference : Can J Hosp Pharm ; 53: 338-345. 2000

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products

List of drugs
InjectionEtoposide Anticancer drug
Stability in solutions Glass Sodium chloride 0,9% 0,2 mg/ml 24°C Light
22 Day
Stability in solutions Glass Sodium chloride 0,9% 0,2 mg/ml 4°C Protect from light
14 Day
Stability in solutions Glass Sodium chloride 0,9% 0,3 mg/ml 24°C Light
2 Day
Stability in solutions Glass Sodium chloride 0,9% 0,3 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass Sodium chloride 0,9% 0,4 mg/ml 24°C Light
24 Hour
Stability in solutions Glass Sodium chloride 0,9% 0,4 mg/ml 4°C Protect from light
2 Day
Stability in solutions Glass Sodium chloride 0,9% 10 mg/ml 24°C Light
5 Day
Stability in solutions Glass Sodium chloride 0,9% 10 mg/ml 4°C Protect from light
7 Day
Stability in solutions Glass Sodium chloride 0,9% 12 mg/ml 24°C Light
7 Day
Stability in solutions Glass Sodium chloride 0,9% 12 mg/ml 4°C Protect from light
14 Day

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