Last update :
22/01/2021
References   References 149  
Type : Journal

Research teams : Poitiers - Université de Poitiers, Faculté de Médecine et Pharmacie
Authors : Rochard E, Barthes D, Courtois P.
Title : Stability of cisplatin in ethylene vinylacetate portable infusion-pump reservoirs.
Reference : J Clin Pharm Ther ; 17: 315-318. 1992

Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 
Degradation products not observed in real conditions

List of drugs
InjectionCisplatin Anticancer drug
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 0,5 & 0,9 mg/ml 22°C Protect from light
28 Day
Stability in solutions Ethylene vinyl acetate Sodium chloride 0,9% 0,5 & 0,9 mg/ml 35°C Protect from light
28 Day

  Mentions Légales