Last update :
28/04/2024
References   References 14  
Type : Journal

Research teams : Houston - M.D.Anderson Cancer Center
Authors : Gilbert DL, Trissel LA, Martinez JF.
Title : Compatibility of ciprofloxacin lactate with sodium bicarbonate during simulated Y-site administration.
Reference : Am J Health-Syst Pharm ; 54: 1193-1195. 1997

Level of Evidence : 
Physical stability : 
Chemical stability : 
Other methods : 
Comments : 

List of drugs
InjectionCiprofloxacin lactate Antibiotic
Factors which affect stability Solvent NaHCO3 Induces Degradation
Incompatible 2 mg/ml + InjectionSodium bicarbonate 8,4 >> 84 mg/ml + Sodium chloride 0,9%
Incompatible 1 mg/ml + InjectionSodium bicarbonate 8,4 >> 42 mg/ml + Sodium chloride 0,9%
Incompatible 1 mg/ml + InjectionSodium bicarbonate 63 & 84 mg/ml + Sodium chloride 0,9%
Incompatible 2 mg/ml + InjectionSodium bicarbonate 63 & 84 mg/ml + Glucose 5%
Incompatible 2 mg/ml + InjectionSodium bicarbonate 8,4 >> 42 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionSodium bicarbonate 63 & 84 mg/ml + Glucose 5%
Incompatible 1 mg/ml + InjectionSodium bicarbonate 8,4 >> 42 mg/ml + Glucose 5%
InjectionSodium bicarbonate Electrolyte
Incompatible 8,4 >> 84 mg/ml + InjectionCiprofloxacin lactate 2 mg/ml + Sodium chloride 0,9%
Incompatible 8,4 >> 42 mg/ml + InjectionCiprofloxacin lactate 1 mg/ml + Sodium chloride 0,9%
Incompatible 63 & 84 mg/ml + InjectionCiprofloxacin lactate 1 mg/ml + Sodium chloride 0,9%
Incompatible 63 & 84 mg/ml + InjectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Incompatible 8,4 >> 42 mg/ml + InjectionCiprofloxacin lactate 2 mg/ml + Glucose 5%
Incompatible 63 & 84 mg/ml + InjectionCiprofloxacin lactate 1 mg/ml + Glucose 5%
Incompatible 8,4 >> 42 mg/ml + InjectionCiprofloxacin lactate 1 mg/ml + Glucose 5%

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