Last update :
18/04/2024
References   References 1349  
Type : Journal

Research teams : Bentley - University of technology, Department of Pharmacy
Authors : Sanburg AL, LyndonRC, Sunderland B.
Title : Effects of freezing, long term storage and microwave thawing on the stability of three antibiotics reconstituted in minibags.
Reference : Aust J Hosp Pharm ; 17: 31-34. 1987

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
InjectionCloxacillin sodium Antibiotic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 20 mg/ml -27°C Protect from light
270 Day
Stability in solutions Polyvinyl chloride Glucose 5% 20 mg/ml -27°C Protect from light
90 Day
InjectionFlucloxacillin sodium Antibiotic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 20 mg/ml -27°C Protect from light
270 Day
Stability in solutions Polyvinyl chloride Glucose 5% 20 mg/ml -27°C Protect from light
90 Day

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