Last update :
03/05/2024
References   References 1287  
Type : Journal

Research teams : Oullins - Laboratoire Lederlé, Recherche et Développement
Authors : Lecompte D, Bousselet M, Gayrard D, Poitou P.
Title : Stability study of reconstituted and diluted solutions of calcium folinate.
Reference : Pharm Ind ; 53: 90-94. 1991

Level of Evidence : 
Level of evidence B
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement 
Comments : 
Degradation products identified and quantified
No visual inspection

List of drugs
InjectionFolinate calcium Cytoprotective
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 & 1,5 mg/ml 25°C Protect from light
4 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 1 & 1,5 mg/ml 4°C Protect from light
4 Day

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