Last update :
15/04/2024
References   References 1275  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, Varrin S, Yannicelli D, Law S.
Title : Stability of meropenem in saline and dextrose solutions and compatibility with potassium chloride.
Reference : Can J Hosp Pharm ; 51: 156-168. 1998

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 
No comments for the degradation products

List of drugs
InjectionMeropenem Antibiotic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml -20°C Protect from light
33 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml 23°C Protect from light
22 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 1 mg/ml 4°C Protect from light
10 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 22 mg/ml -20°C Protect from light
11 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 22 mg/ml 23°C Protect from light
17 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 22 mg/ml 4°C Protect from light
4 Day
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml -20°C Protect from light
1 Day
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 23°C Protect from light
4 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 1 mg/ml 4°C Protect from light
1 Day
Stability in solutions Polyvinyl chloride Glucose 5% 22 mg/ml -20°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride Glucose 5% 22 mg/ml 23°C Protect from light
8 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 22 mg/ml 4°C Protect from light
2 Day

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