Last update :
28/04/2024
References   References 121  
Type : Journal

Research teams : Toronto - Sunnybrook Health Sciences Center
Authors : Walker SE, Iazzetta J, Lau DWC.
Title : Stability of sulfite free high potency morphine sulfate solutions in portable infusion pump cassettes.
Reference : Can J Hosp Pharm ; 42: 195-200. 1989

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 90% of the initial concentration
Other methods : 
PH measurement 
Comments : 

List of drugs
InjectionMorphine sulfate Analgesic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 10 mg/ml 23°C Not specified
31 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 10 mg/ml 4°C Not specified
31 Day
Stability in solutions Polyvinyl chloride Glucose 5% 10 mg/ml 23°C Not specified
31 Day
Stability in solutions Polyvinyl chloride Glucose 5% 10 mg/ml 4°C Protect from light
31 Day
Stability in solutions Polyvinyl chloride None 25 & 50 mg/ml 23°C Not specified
31 Day
Stability in solutions Polyvinyl chloride None 25 & 50 mg/ml 4°C Protect from light
31 Day

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