Last update :
21/01/2021
References   References 1155  
Type : Journal

Research teams : London - School of Pharmacy and Chemistry
Authors : Wright MP, Newton JM.
Title : Stability of methotrexate injection in prefilled plastic disposable syringes.
Reference : Int J Pharm ; 45: 237-244. 1988

Level of Evidence : 
Level of evidence C
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
Degradation products detected but not quantified

List of drugs
InjectionMethotrexate sodium Anticancer drug
Factors which affect stability Storage Light Induces Degradation
Stability in solutions Polypropylen Syringe Water for Injection 50 mg/ml 25°C Protect from light
70 Day

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