Last update :
05/12/2025
References   References 4971  
Type : Journal
Web link : https://doi.org/10.1016/j.jpba.2025.116876

Research teams : Porto Alegre - Pharmacy School of Federal University of Rio Grande do Sul
Authors : Coelho Mendes M, Fanfa Machioli L, Carlos G, Franco de Oliveira T, Loureiro Mendez A S.
Title : Stability of the antibiotic ceftaroline fosamil with focus on degradation products and decomposition pathways – Integrative analysis by LC-DAD, ESI-QTOF and in silico prediction
Reference : J Pharm Biomed Anal ; 262: 116876. 2025

Level of Evidence : 
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Other methods : 
PH measurement 
Comments : 
Repeatability / reproducibility / standard range: results not provided or results outside specified values
No visual inspection

List of drugs
injectionCeftaroline fosamil Antibiotic
Factors which affect stability Solvent Glucose 5% Induces Reduced stability
Factors which affect stability Temperature 4°C Induces Enhanced stability

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