Last update :
21/01/2026
References   References 183  
Type : Journal
Web link : http://www.ajhp.org/cgi/content/abstract/49/9/2223

Research teams : Charleston - Medical University of South Carolina
Authors : Bosso JA, Prince RA, Fox JL.
Title : Stability of ondansetron hydrochloride in injectable solutions at -20, 5, and 25°C.
Reference : Am J Hosp Pharm ; 49: 2223-2225. 1992

Level of Evidence : 
Level of evidence B
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Results with high coefficient of variation or not provided, or lack of duplicate analysis of each point

List of drugs
injectionOndansetron hydrochloride Antiemetic
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,03 & 0,3 mg/ml -20°C Protect from light
90 Day
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,03 & 0,3 mg/ml 25°C Light
48 Hour
Stability in solutions Polyvinyl chloride Sodium chloride 0,9% 0,03 & 0,3 mg/ml 4°C Protect from light
14 Day
Stability in solutions Polyvinyl chloride Glucose 5% 0,03 & 0,3 mg/ml -20°C Protect from light
90 Day
Stability in solutions Polyvinyl chloride Glucose 5% 0,03 & 0,3 mg/ml 25°C Light
48 Hour
Stability in solutions Polyvinyl chloride Glucose 5% 0,03 & 0,3 mg/ml 4°C Protect from light
14 Day

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