Last update :
08/05/2024
References   References 702  
Type : Journal
Web link : http://www.john-libbey-eurotext.fr/fr/revues/bio_rech/jpc/e-docs/00/02/71/13/article.md?type=text.html

Research teams : Reims - University Hospital Robert Debré, Pharmacy Department
Authors : Biellmann-Berlaud V, Willemin JC.
Title : Stability of vancomycin in polyolefine or PVC bags and glass vials.
Reference : J Pharm Clin ; 17: 145-148. 1998

Level of Evidence : 
Level of evidence D
Physical stability : 
Visual examination 
Chemical stability : 
Stability defined as 90% of the initial concentration
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Other methods : 
PH measurement 
Comments : 
Stability indicating capability inadequately assessed
Increased concentration unexplained
No comments for the degradation products

List of drugs
InjectionVancomycin hydrochloride Antibiotic
Stability in solutions Glass NaCl 0,9% or Glucose 5% 2 mg/ml 2-8°C Protect from light
7 Day
Stability in solutions Glass NaCl 0,9% or Glucose 5% 2 mg/ml 25°C Protect from light
48 Hour
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 2 mg/ml 2-8°C Protect from light
7 Day
Stability in solutions Polyvinyl chloride NaCl 0,9% or Glucose 5% 2 mg/ml 25°C Protect from light
48 Hour
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 2 mg/ml 2-8°C Protect from light
7 Day
Stability in solutions Polyolefine NaCl 0,9% or Glucose 5% 2 mg/ml 25°C Protect from light
48 Hour

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