Last update :
18/04/2024
References   References 3918  
Type : Journal
Web link : http://opp.sagepub.com/content/22/6/749.abstract

Research teams : Incheon - Yonsei University, College of Pharmacy
Authors : Sarakbi I, Krämer I.
Title : Compatibility of epirubicin-loaded DC bead™ with different non-ionic contrast media.
Reference : J Oncol Pharm Practice ; 22: 749-756. 2016

Level of Evidence : 
Level of evidence A
Physical stability : 
Chemical stability : 
High Performance Liquid Chromatography - Diode Array detector (HPLD-DAD)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Degradation products not observed in real conditions

List of drugs
InjectionEpirubicin hydrochloride Anticancer drug
InjectionIodixanol Radiocontrast agent
InjectionIohexol Radiocontrast agent
InjectionIomeprol Radiocontrast agent
InjectionIopromide Radiocontrast agent
Stability of mixtures
Polypropylene DC Beads® 2-8°C Protect from light
Injection Epirubicin hydrochloride 25 mg/ml
Injection Iohexol 300 mg I/ml
7 Day
Polypropylene DC Beads® 2-8°C Protect from light
Injection Epirubicin hydrochloride 25 mg/ml
Injection Iomeprol 300 mg I/ml
7 Day
Polypropylene DC Beads® 2-8°C Protect from light
Injection Epirubicin hydrochloride 25 mg/ml
Injection Iopromide 300 mg I/ml
7 Day
Polypropylene DC Beads® 2-8°C Protect from light
Injection Epirubicin hydrochloride 25 mg/ml
Injection Iodixanol 320 mg I/ml
7 Day

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