Last update :
28/04/2024
References   References 3895  
Type : Journal
Web link : https://doi.org/10.1177/1060028016649598

Research teams : Singapore - Department of Pharmacy, Faculty of Science, National University of Singapore
Authors : Lim Tze-Peng, Kim-Hor Hee D, Lee W, Qi-Min Teo J, Cai Y,Yu-Hng Chia S, Yee-Kiat Leaw J, Jing-Yi Lee S, Soon-U Lee L, Kwa A.L.
Title : Physicochemical Stability Study of Polymyxin B in Various Infusion Solutions for Administration to Critically Ill Patients
Reference : Ann Pharmacotherapy ; 50: 790-792. 2016

Level of Evidence : 
Level of evidence A
Physical stability : 
Chemical stability : 
Stability defined as 95% of the initial concentration
Other methods : 
PH measurement Measurement of osmolality 
Comments : 
No comments for the degradation products
No visual inspection

List of drugs
InjectionPolymyxine B Antibiotic
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 2 mg/ml 25-30°C Not specified
24 Hour
Stability in solutions Polypropylen Syringe NaCl 0,9% or Glucose 5% 2 mg/ml 4°C Not specified
168 Hour
Stability in solutions Polypropylen Syringe NaCl 0,45% Glucose 5% 2 mg/ml 25-30°C Not specified
24 Hour
Stability in solutions Polypropylen Syringe NaCl 0,45% Glucose 5% 2 mg/ml 4°C Not specified
168 Hour

  Mentions Légales