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References   References 3804  
Type : Journal
Web link : http://dx.doi.org/10.1136/ejhpharm-2014-000558
Research teams : Ferrara - Department of Chemical and Pharmaceutical Sciences, University of Ferrara
Authors : Lazzarini R, Salvadori S, Trapella C, Guerrini R, Marzola E, Pasini G, Dalpiaz A.
Title : Physicochemical stability of cabazitaxel and docetaxel solutions.
Reference : EJHP ;22:150-155. 2014
Level of Evidence : 
Level of evidence A
Physical stability : 
Visual examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
High Performance Liquid Chromatography - mass spectrometry (HPLC-MS)
Stability defined as 95% of the initial concentration
Other methods : 
Comments : 
Degradation products not observed in real conditions
List of drugs
InjectionCabazitaxel Anticancer drug
Stability in solutions Glass None 10 mg/ml 4°C Protect from light
28 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0,15 mg/ml 25°C Protect from light
28 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0,15 mg/ml 4°C Protect from light
28 Day
InjectionDocetaxel Anticancer drug
Stability in solutions Polyolefine Sodium chloride 0,9% 0,30 mg/ml 25°C Protect from light
28 Day
Stability in solutions Polyolefine Sodium chloride 0,9% 0,30 mg/ml 4°C Protect from light
28 Day
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