Last update :
03/05/2024
References   References 3415  
Type : Journal
Web link : http://www.omicsonline.org/2153-2435/2153-2435-abstract.php?abstract_id=11345
Icone.pdf
2132Ko

Research teams : Créteil - Henri Mondor University Hospital, Department of Pharmacy
Authors : d?Hayer B, Vieillard V, Astier A, Paul M
Title : Stability-Indicating HPLC Assay and Stability Study Over Two Years of Morphine Hydrochloride Diluted Solutions in Polypropylene Syringes
Reference : Pharmaceut Anal Acta ; 4: 205 2013

Level of Evidence : 
Level of evidence A+
Physical stability : 
Visual examination Microscopic examination 
Chemical stability : 
High Performance Liquid Chromatography - ultraviolet detector (HPLC-UV)
Stability defined as 95% of the initial concentration
Other methods : 
Water loss by evaporation Measurement of osmolality 
Comments : 

List of drugs
InjectionMorphine hydrochloride Analgesic
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0.33 mg/ml 2-8°C Protect from light
730 Day
Stability in solutions Polypropylen Syringe Sodium chloride 0,9% 0.33 mg/ml 22°C Protect from light
730 Day

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